7β-Hydroxy­artemisinin

نویسندگان

  • Paulo B. Carvalho
  • Bo Liu
  • Yunshan Wu
  • John S. Williamson
  • Mitchell A. Avery
چکیده

CRYSTALS OF THE TITLE COMPOUND [SYSTEMATIC NAME: (3R,6R,7S,8aR,9R,12aR)-7-hydr-oxy-3,6,9-trimethyl-octa-hydro-3,12-ep-oxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one], C(15)H(22)O(6), were obtained from microbial transformation of artemisinin by a culture of Cunninghamella elegans. The stereochemistry of the compound is consistent with the spectroscopic findings in previously published works. A weak O-H⋯O hydrogen bond occurs in the crystal structure, together with intermolecular C-H⋯O hydrogen bonds.

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عنوان ژورنال:

دوره 64  شماره 

صفحات  -

تاریخ انتشار 2008